Ephrin type-B receptor 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P29323. Use UniProt P29323 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P29323 as the stable identity anchor, then attach disease evidence before program review.
Ephrin type-B receptor 2
Review this target as Ephrin type-B receptor 2, mapped to UniProt P29323. Sequence length is 1055 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Ephrin type-B receptor 2 as ChEMBL target CHEMBL3290, mapped to UniProt P29323. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Ephrin type-B receptor 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P29323 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ephrin type-B receptor 2 |
| UniProt Accession | P29323 |
| Component Type | Protein |
| Sequence Length | 1055 aa |
Ephrin type-B receptor 2
Review this target as Ephrin type-B receptor 2, mapped to UniProt P29323. Sequence length is 1055 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5416410 | 9.41 | Kd | 0.39 | Approved |
| CHEMBL566515 | 8.92 | IC50 | 1.2 | Preclinical |
| CHEMBL400402 | 8.7 | Kd | 2.0 | Preclinical |
| CHEMBL3752910 | 8.6 | IC50 | 2.5 | Preclinical |
| CHEMBL1421 | 8.57 | IC50 | 2.7 | Approved |
| CHEMBL4568087 | 8.54 | IC50 | 2.9 | Preclinical |
| CHEMBL1230609 | 8.41 | Kd | 3.9 | Clinical |
| CHEMBL1421 | 8.41 | Kd | 3.9 | Approved |
| CHEMBL5416410 | 8.36 | IC50 | 4.4 | Approved |
| CHEMBL249097 | 8.15 | Kd | 7.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 242 | 78 | 6.1 |
| assay format | 32 | 8 | 7.3 |
| cell-based format | 26 | 7 | 6.6 |
| subcellular format | 6 | 19 | 6.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |