Ectonucleoside triphosphate diphosphohydrolase 2 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt O35795. Use UniProt O35795 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O35795 as the stable identity anchor, then attach disease evidence before program review.
Ectonucleoside triphosphate diphosphohydrolase 2
Review this target as Ectonucleoside triphosphate diphosphohydrolase 2, mapped to UniProt O35795. Sequence length is 495 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Ectonucleoside triphosphate diphosphohydrolase 2 as ChEMBL target CHEMBL3300, mapped to UniProt O35795. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Ectonucleoside triphosphate diphosphohydrolase 2 is the right protein anchor across sources, using UniProt O35795 as the stable mapping.
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| Preferred Name | Ectonucleoside triphosphate diphosphohydrolase 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | O35795 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ectonucleoside triphosphate diphosphohydrolase 2 |
| UniProt Accession | O35795 |
| Component Type | Protein |
| Sequence Length | 495 aa |
Ectonucleoside triphosphate diphosphohydrolase 2
Review this target as Ectonucleoside triphosphate diphosphohydrolase 2, mapped to UniProt O35795. Sequence length is 495 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL271673 | 4.75 | Ki | 18000.0 | Preclinical |
| CHEMBL597197 | 4.72 | Ki | 19100.0 | Preclinical |
| CHEMBL223344 | 4.62 | Ki | 24200.0 | Preclinical |
| CHEMBL4744335 | 4.62 | Ki | 24200.0 | Preclinical |
| CHEMBL256057 | 4.45 | Ki | 35800.0 | Preclinical |
| CHEMBL477339 | 4.36 | Ki | 44200.0 | Preclinical |
| CHEMBL265502 | 4.18 | Ki | 65400.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 5 | 4.6 |
| single protein format | 4 | 4 | 4.5 |