CDK6/cyclin D2 · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q00534. Use UniProt Q00534 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q00534 as the stable identity anchor, then attach disease evidence before program review.
Cyclin-dependent kinase 6
Review this target as CDK6/cyclin D2, mapped to UniProt Q00534. ChEMBL maps the protein component as Cyclin-dependent kinase 6. Sequence length is 326 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats CDK6/cyclin D2 as ChEMBL target CHEMBL3301386, mapped to UniProt Q00534. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | CDK6/cyclin D2 |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | Q00534 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cyclin-dependent kinase 6 |
| UniProt Accession | Q00534 |
| Component Type | Protein |
| Sequence Length | 326 aa |
Cyclin-dependent kinase 6
Review this target as CDK6/cyclin D2, mapped to UniProt Q00534. ChEMBL maps the protein component as Cyclin-dependent kinase 6. Sequence length is 326 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL189963 | 8.05 | IC50 | 9.0 | Approved |
| CHEMBL361708 | 6.16 | IC50 | 700.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 1 | 7.9 |
| protein complex format | 4 | 2 | 7.0 |