Phospholipase D1 · SINGLE PROTEIN · Rattus norvegicus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P70496. Use UniProt P70496 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P70496 as the stable identity anchor, then attach disease evidence before program review.
Phospholipase D1
Review this target as Phospholipase D1, mapped to UniProt P70496. Sequence length is 1074 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Phospholipase D1 as ChEMBL target CHEMBL3308939, mapped to UniProt P70496. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Phospholipase D1 is the right protein anchor across sources, using UniProt P70496 as the stable mapping.
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| Preferred Name | Phospholipase D1 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P70496 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phospholipase D1 |
| UniProt Accession | P70496 |
| Component Type | Protein |
| Sequence Length | 1074 aa |
Phospholipase D1
Review this target as Phospholipase D1, mapped to UniProt P70496. Sequence length is 1074 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL245621 | 7.96 | IC50 | 11.0 | Clinical |
| CHEMBL398567 | 7.48 | IC50 | 33.0 | Preclinical |
| CHEMBL492572 | 6.48 | IC50 | 331.0 | Preclinical |
| CHEMBL1213144 | 6.11 | IC50 | 780.0 | Preclinical |
| CHEMBL1213141 | 6.1 | IC50 | 790.0 | Preclinical |
| CHEMBL1213100 | 6.06 | IC50 | 870.0 | Preclinical |
| CHEMBL1213069 | 6.04 | IC50 | 910.0 | Preclinical |
| CHEMBL1213097 | 6.04 | IC50 | 910.0 | Preclinical |
| CHEMBL398568 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL492797 | 6.0 | IC50 | 1000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 21 | 5.9 |