Thymidine kinase · SINGLE PROTEIN · Varicella-zoster virus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P0C0E6. Use UniProt P0C0E6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P0C0E6 as the stable identity anchor, then attach disease evidence before program review.
Thymidine kinase
Review this target as Thymidine kinase, mapped to UniProt P0C0E6. Sequence length is 341 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Thymidine kinase as ChEMBL target CHEMBL3308966, mapped to UniProt P0C0E6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Thymidine kinase |
| Target Type | SINGLE PROTEIN |
| Organism | Varicella-zoster virus |
| UniProt | P0C0E6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Thymidine kinase |
| UniProt Accession | P0C0E6 |
| Component Type | Protein |
| Sequence Length | 341 aa |
Thymidine kinase
Review this target as Thymidine kinase, mapped to UniProt P0C0E6. Sequence length is 341 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL565370 | 5.57 | IC50 | 2700.0 | Preclinical |
| CHEMBL344738 | 5.48 | IC50 | 3300.0 | Preclinical |
| CHEMBL585089 | 4.89 | IC50 | 13000.0 | Preclinical |
| CHEMBL565998 | 4.42 | IC50 | 38000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 4 | 5.1 |