AMP-binding enzyme family protein · SINGLE PROTEIN · Yersinia pestis
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As of 2026-09-14Protein identity stays anchored to UniProt Q56950. Use UniProt Q56950 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q56950 as the stable identity anchor, then attach disease evidence before program review.
Salicyl-AMP ligase YbtE
Review this target as AMP-binding enzyme family protein, mapped to UniProt Q56950. ChEMBL maps the protein component as Salicyl-AMP ligase YbtE. Sequence length is 525 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats AMP-binding enzyme family protein as ChEMBL target CHEMBL3308969, mapped to UniProt Q56950. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether AMP-binding enzyme family protein is the right protein anchor across sources, using UniProt Q56950 as the stable mapping.
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| Preferred Name | AMP-binding enzyme family protein |
| Target Type | SINGLE PROTEIN |
| Organism | Yersinia pestis |
| UniProt | Q56950 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Salicyl-AMP ligase YbtE |
| UniProt Accession | Q56950 |
| Component Type | Protein |
| Sequence Length | 525 aa |
Salicyl-AMP ligase YbtE
Review this target as AMP-binding enzyme family protein, mapped to UniProt Q56950. ChEMBL maps the protein component as Salicyl-AMP ligase YbtE. Sequence length is 525 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL371502 | 8.97 | Ki | 1.08 | Preclinical |
| CHEMBL371502 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL255008 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL258440 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL404731 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL257574 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL444374 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL255435 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL402834 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL256080 | 6.3 | IC50 | 500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 29 | 6.4 |