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Target Snapshot

CHEMBL3308979 Target Snapshot

CDGSH iron-sulfur domain-containing protein 1 · SINGLE PROTEIN · Rattus norvegicus

3Compounds
1Assays
2Approved Drugs
3.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt B0K020. Use UniProt B0K020 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt B0K020 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats CDGSH iron-sulfur domain-containing protein 1 as ChEMBL target CHEMBL3308979, mapped to UniProt B0K020. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
CDGSH iron-sulfur domain-containing protein 1
SINGLE PROTEIN · Rattus norvegicus
As of 2026-09-13
ChEMBL target ID
CHEMBL3308979
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
B0K020
CDGSH iron-sulfur domain-containing protein 1
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether CDGSH iron-sulfur domain-containing protein 1 is the right protein anchor across sources, using UniProt B0K020 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelCDGSH iron-sulfur domain-containing protein 1
UniProt AccessionB0K020
Component TypeProtein
Sequence Length108 aa

CDGSH iron-sulfur domain-containing protein 1

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as CDGSH iron-sulfur domain-containing protein 1, mapped to UniProt B0K020. Sequence length is 108 aa.

Mapped IDB0K020
Review nameCDGSH iron-sulfur domain-containing protein 1
OrganismRattus norvegicus
Clinical Profile

Clinical Phase Distribution

2
Approved
Assay Mix

Activity Type Distribution

IC503.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL602048 6.05 IC50 900.0 Preclinical
CHEMBL595 6.0 IC50 1000.0 Approved
CHEMBL121 5.96 IC50 1100.0 Approved
Distribution

pChEMBL Value Distribution

0
5.0
1
5.5
2
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

PIOGLITAZONE
CHEMBL595
Approved 1999
Assay Landscape

Assay Landscape

1
Total Assays
3
Tested Compounds
1
Assay Types
Binding — 1 assays, 3 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 1 3 6.0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine