Use UniProt B0K020 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3308979 Target Snapshot
CDGSH iron-sulfur domain-containing protein 1 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt B0K020. Use UniProt B0K020 as the stable identity anchor, then attach disease evidence before program review.
CDGSH iron-sulfur domain-containing protein 1
Review this target as CDGSH iron-sulfur domain-containing protein 1, mapped to UniProt B0K020. Sequence length is 108 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats CDGSH iron-sulfur domain-containing protein 1 as ChEMBL target CHEMBL3308979, mapped to UniProt B0K020. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether CDGSH iron-sulfur domain-containing protein 1 is the right protein anchor across sources, using UniProt B0K020 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | CDGSH iron-sulfur domain-containing protein 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | B0K020 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | CDGSH iron-sulfur domain-containing protein 1 |
| UniProt Accession | B0K020 |
| Component Type | Protein |
| Sequence Length | 108 aa |
CDGSH iron-sulfur domain-containing protein 1
How to read this target
Review this target as CDGSH iron-sulfur domain-containing protein 1, mapped to UniProt B0K020. Sequence length is 108 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL602048 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL595 | 6.0 | IC50 | 1000.0 | Approved |
| CHEMBL121 | 5.96 | IC50 | 1100.0 | Approved |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 1 assays, 3 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 3 | 6.0 |