Activin receptor type-1 · SINGLE PROTEIN · Mus musculus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P37172. Use UniProt P37172 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P37172 as the stable identity anchor, then attach disease evidence before program review.
Activin receptor type-1
Review this target as Activin receptor type-1, mapped to UniProt P37172. Sequence length is 509 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Activin receptor type-1 as ChEMBL target CHEMBL3309042, mapped to UniProt P37172. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Activin receptor type-1 is the right protein anchor across sources, using UniProt P37172 as the stable mapping.
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| Preferred Name | Activin receptor type-1 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P37172 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Activin receptor type-1 |
| UniProt Accession | P37172 |
| Component Type | Protein |
| Sequence Length | 509 aa |
Activin receptor type-1
Review this target as Activin receptor type-1, mapped to UniProt P37172. Sequence length is 509 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4283638 | 8.1 | EC50 | 8.0 | Preclinical |
| CHEMBL513147 | 7.85 | EC50 | 14.0 | Preclinical |
| CHEMBL4288921 | 7.04 | EC50 | 91.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 3 | 7.7 |