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Target Snapshot

CHEMBL3309106 Target Snapshot

Taste receptor type 2 member 16 · SINGLE PROTEIN · Homo sapiens

27Compounds
56Assays
1Approved Drugs
28.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt Q9NYV7. Use UniProt Q9NYV7 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9NYV7 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Taste receptor type 2 member 16 as ChEMBL target CHEMBL3309106, mapped to UniProt Q9NYV7. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Taste receptor type 2 member 16
SINGLE PROTEIN · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL3309106
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
Q9NYV7
Taste receptor type 2 member 16
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Taste receptor type 2 member 16 is the right protein anchor across sources, using UniProt Q9NYV7 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelTaste receptor type 2 member 16
UniProt AccessionQ9NYV7
Component TypeProtein
Sequence Length291 aa

Taste receptor type 2 member 16

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Taste receptor type 2 member 16, mapped to UniProt Q9NYV7. Sequence length is 291 aa.

Mapped IDQ9NYV7
Review nameTaste receptor type 2 member 16
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

1
Approved
Assay Mix

Activity Type Distribution

IC501.0
EC5027.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL434 8.31 EC50 4.9 Approved
CHEMBL4105357 6.68 EC50 210.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
2
6.5
0
7.0
0
7.5
1
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

ISOPROTERENOL
CHEMBL434
Approved 1956
Assay Landscape

Assay Landscape

56
Total Assays
9
Tested Compounds
2
Assay Types
Functional — 54 assays, 9 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 54 9 7.2
Binding — 2 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 2 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine