Use UniProt Q79EC5 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3313836 Target Snapshot
Toxin ParE · SINGLE PROTEIN · Escherichia coli
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As of 2026-09-15Protein identity stays anchored to UniProt Q79EC5. Use UniProt Q79EC5 as the stable identity anchor, then attach disease evidence before program review.
Toxin ParE
Review this target as Toxin ParE, mapped to UniProt Q79EC5. Sequence length is 103 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Toxin ParE as ChEMBL target CHEMBL3313836, mapped to UniProt Q79EC5. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Toxin ParE |
| Target Type | SINGLE PROTEIN |
| Organism | Escherichia coli |
| UniProt | Q79EC5 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Toxin ParE |
| UniProt Accession | Q79EC5 |
| Component Type | Protein |
| Sequence Length | 103 aa |
Toxin ParE
How to read this target
Review this target as Toxin ParE, mapped to UniProt Q79EC5. Sequence length is 103 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3314585 | 9.92 | IC50 | 0.12 | Preclinical |
| CHEMBL3314580 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL3314550 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL3314532 | 7.62 | IC50 | 24.0 | Preclinical |
| CHEMBL3314588 | 7.46 | IC50 | 35.0 | Preclinical |
| CHEMBL3314569 | 7.44 | IC50 | 36.0 | Preclinical |
| CHEMBL3314589 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL3314547 | 7.39 | IC50 | 41.0 | Preclinical |
| CHEMBL3314568 | 7.38 | IC50 | 42.0 | Preclinical |
| CHEMBL3314566 | 7.37 | IC50 | 43.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 56 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 56 | 7.0 |