5-lipoxygenase · SINGLE PROTEIN · Solanum tuberosum
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As of 2026-09-14Protein identity stays anchored to UniProt O49150. Use UniProt O49150 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O49150 as the stable identity anchor, then attach disease evidence before program review.
Lipoxygenase
Review this target as 5-lipoxygenase, mapped to UniProt O49150. ChEMBL maps the protein component as Lipoxygenase. Sequence length is 864 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 5-lipoxygenase as ChEMBL target CHEMBL3317, mapped to UniProt O49150. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 5-lipoxygenase |
| Target Type | SINGLE PROTEIN |
| Organism | Solanum tuberosum |
| UniProt | O49150 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Lipoxygenase |
| UniProt Accession | O49150 |
| Component Type | Protein |
| Sequence Length | 864 aa |
Lipoxygenase
Review this target as 5-lipoxygenase, mapped to UniProt O49150. ChEMBL maps the protein component as Lipoxygenase. Sequence length is 864 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL204796 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL579022 | 6.55 | IC50 | 280.0 | Preclinical |
| CHEMBL194297 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL364739 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL204769 | 6.5 | IC50 | 320.0 | Preclinical |
| CHEMBL205120 | 6.5 | IC50 | 320.0 | Preclinical |
| CHEMBL571852 | 6.5 | IC50 | 320.0 | Preclinical |
| CHEMBL578389 | 6.43 | IC50 | 370.0 | Preclinical |
| CHEMBL197573 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL203459 | 6.0 | IC50 | 1000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 19 | 6.0 |