Cytochrome P450 3A1 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P04800. Use UniProt P04800 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P04800 as the stable identity anchor, then attach disease evidence before program review.
Cytochrome P450 3A1
Review this target as Cytochrome P450 3A1, mapped to UniProt P04800. Sequence length is 504 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cytochrome P450 3A1 as ChEMBL target CHEMBL3323, mapped to UniProt P04800. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cytochrome P450 3A1 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P04800 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cytochrome P450 3A1 |
| UniProt Accession | P04800 |
| Component Type | Protein |
| Sequence Length | 504 aa |
Cytochrome P450 3A1
Review this target as Cytochrome P450 3A1, mapped to UniProt P04800. Sequence length is 504 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL208047 | 5.85 | IC50 | 1400.0 | Preclinical |
| CHEMBL472975 | 5.75 | IC50 | 1800.0 | Preclinical |
| CHEMBL473375 | 5.7 | IC50 | 2000.0 | Preclinical |
| CHEMBL475163 | 5.7 | IC50 | 2000.0 | Preclinical |
| CHEMBL515086 | 5.68 | IC50 | 2100.0 | Preclinical |
| CHEMBL447959 | 5.66 | IC50 | 2200.0 | Preclinical |
| CHEMBL473364 | 5.55 | IC50 | 2800.0 | Preclinical |
| CHEMBL516064 | 5.47 | IC50 | 3400.0 | Preclinical |
| CHEMBL464300 | 5.4 | IC50 | 4000.0 | Preclinical |
| CHEMBL3216038 | 5.16 | IC50 | 7000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 0 | — |
| assay format | 1 | 0 | — |
| microsome format | 1 | 11 | 5.5 |