Beta-lactamase L1 · SINGLE PROTEIN · Stenotrophomonas maltophilia
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As of 2026-09-14Protein identity stays anchored to UniProt P52700. Use UniProt P52700 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P52700 as the stable identity anchor, then attach disease evidence before program review.
Metallo-beta-lactamase L1 type 3
Review this target as Beta-lactamase L1, mapped to UniProt P52700. ChEMBL maps the protein component as Metallo-beta-lactamase L1 type 3. Sequence length is 290 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-lactamase L1 as ChEMBL target CHEMBL3326, mapped to UniProt P52700. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Beta-lactamase L1 is the right protein anchor across sources, using UniProt P52700 as the stable mapping.
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| Preferred Name | Beta-lactamase L1 |
| Target Type | SINGLE PROTEIN |
| Organism | Stenotrophomonas maltophilia |
| UniProt | P52700 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Metallo-beta-lactamase L1 type 3 |
| UniProt Accession | P52700 |
| Component Type | Protein |
| Sequence Length | 290 aa |
Metallo-beta-lactamase L1 type 3
Review this target as Beta-lactamase L1, mapped to UniProt P52700. ChEMBL maps the protein component as Metallo-beta-lactamase L1 type 3. Sequence length is 290 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL215590 | 8.68 | Ki | 2.1 | Preclinical |
| CHEMBL217877 | 7.92 | Ki | 12.0 | Preclinical |
| CHEMBL386173 | 7.92 | Ki | 12.0 | Preclinical |
| CHEMBL3586478 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL385145 | 7.58 | Ki | 26.0 | Preclinical |
| CHEMBL3586477 | 7.16 | IC50 | 69.0 | Preclinical |
| CHEMBL25766 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL3586478 | 6.96 | Ki | 110.0 | Preclinical |
| CHEMBL385485 | 6.85 | Ki | 140.0 | Preclinical |
| CHEMBL385075 | 6.82 | Ki | 150.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 10 | 48 | 6.0 |
| assay format | 6 | 10 | 6.5 |