Mas-related G-protein coupled receptor member X1 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q8R4G1. Use UniProt Q8R4G1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8R4G1 as the stable identity anchor, then attach disease evidence before program review.
Mas-related G-protein coupled receptor member X1
Review this target as Mas-related G-protein coupled receptor member X1, mapped to UniProt Q8R4G1. Sequence length is 323 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Mas-related G-protein coupled receptor member X1 as ChEMBL target CHEMBL3341575, mapped to UniProt Q8R4G1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Mas-related G-protein coupled receptor member X1 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q8R4G1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Mas-related G-protein coupled receptor member X1 |
| UniProt Accession | Q8R4G1 |
| Component Type | Protein |
| Sequence Length | 323 aa |
Mas-related G-protein coupled receptor member X1
Review this target as Mas-related G-protein coupled receptor member X1, mapped to UniProt Q8R4G1. Sequence length is 323 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3343995 | 6.99 | IC50 | 103.0 | Preclinical |
| CHEMBL3727438 | 6.8 | IC50 | 157.0 | Preclinical |
| CHEMBL3730717 | 6.73 | IC50 | 187.0 | Preclinical |
| CHEMBL3730500 | 6.68 | IC50 | 209.0 | Preclinical |
| CHEMBL3731811 | 6.66 | IC50 | 220.0 | Preclinical |
| CHEMBL3343989 | 6.52 | EC50 | 300.0 | Preclinical |
| CHEMBL3727861 | 6.48 | IC50 | 334.0 | Preclinical |
| CHEMBL3728505 | 6.34 | IC50 | 460.0 | Preclinical |
| CHEMBL3729794 | 6.31 | IC50 | 492.0 | Preclinical |
| CHEMBL145103 | 6.2 | IC50 | 632.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 6 | 5.5 |
| single protein format | 1 | 1 | 6.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 16 | 5.4 |
| cell-based format | 1 | 16 | 6.2 |