Tyrosine-protein kinase Blk · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P16277. Use UniProt P16277 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P16277 as the stable identity anchor, then attach disease evidence before program review.
Tyrosine-protein kinase Blk
Review this target as Tyrosine-protein kinase Blk, mapped to UniProt P16277. Sequence length is 499 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Tyrosine-protein kinase Blk as ChEMBL target CHEMBL3343, mapped to UniProt P16277. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Tyrosine-protein kinase Blk is the right protein anchor across sources, using UniProt P16277 as the stable mapping.
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| Preferred Name | Tyrosine-protein kinase Blk |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P16277 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tyrosine-protein kinase Blk |
| UniProt Accession | P16277 |
| Component Type | Protein |
| Sequence Length | 499 aa |
Tyrosine-protein kinase Blk
Review this target as Tyrosine-protein kinase Blk, mapped to UniProt P16277. Sequence length is 499 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL288441 | 8.14 | IC50 | 7.3 | Approved |
| CHEMBL2010872 | 8.1 | IC50 | 8.0 | Clinical |
| CHEMBL5416410 | 8.1 | IC50 | 8.0 | Approved |
| CHEMBL388978 | 6.4 | IC50 | 400.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 14 | 3 | 8.1 |
| cell-based format | 6 | 1 | 6.4 |