Gag-Pro polyprotein · SINGLE PROTEIN · Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1)
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As of 2026-09-14Protein identity stays anchored to UniProt P10274. Use UniProt P10274 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P10274 as the stable identity anchor, then attach disease evidence before program review.
Gag-Pro polyprotein
Review this target as Gag-Pro polyprotein, mapped to UniProt P10274. Sequence length is 651 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Gag-Pro polyprotein as ChEMBL target CHEMBL3346, mapped to UniProt P10274. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Gag-Pro polyprotein |
| Target Type | SINGLE PROTEIN |
| Organism | Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) |
| UniProt | P10274 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Gag-Pro polyprotein |
| UniProt Accession | P10274 |
| Component Type | Protein |
| Sequence Length | 651 aa |
Gag-Pro polyprotein
Review this target as Gag-Pro polyprotein, mapped to UniProt P10274. Sequence length is 651 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL272710 | 7.08 | IC50 | 84.0 | Preclinical |
| CHEMBL271706 | 7.06 | IC50 | 88.0 | Preclinical |
| CHEMBL272280 | 7.02 | IC50 | 95.0 | Preclinical |
| CHEMBL271878 | 7.0 | IC50 | 101.0 | Preclinical |
| CHEMBL403182 | 6.99 | IC50 | 102.0 | Preclinical |
| CHEMBL404702 | 6.99 | IC50 | 103.0 | Preclinical |
| CHEMBL403240 | 6.97 | IC50 | 107.0 | Preclinical |
| CHEMBL256022 | 6.95 | IC50 | 113.0 | Preclinical |
| CHEMBL403770 | 6.91 | IC50 | 123.0 | Preclinical |
| CHEMBL256587 | 6.88 | IC50 | 131.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 2 | 5.1 |
| assay format | 1 | 26 | 6.8 |