Acetyl-CoA carboxylase 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q13085. Use UniProt Q13085 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q13085 as the stable identity anchor, then attach disease evidence before program review.
Acetyl-CoA carboxylase 1
Review this target as Acetyl-CoA carboxylase 1, mapped to UniProt Q13085. Sequence length is 2346 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Acetyl-CoA carboxylase 1 as ChEMBL target CHEMBL3351, mapped to UniProt Q13085. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Acetyl-CoA carboxylase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q13085 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Acetyl-CoA carboxylase 1 |
| UniProt Accession | Q13085 |
| Component Type | Protein |
| Sequence Length | 2346 aa |
Acetyl-CoA carboxylase 1
Review this target as Acetyl-CoA carboxylase 1, mapped to UniProt Q13085. Sequence length is 2346 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4875701 | 9.52 | EC50 | 0.3 | Preclinical |
| CHEMBL5918349 | 9.33 | IC50 | 0.47 | Preclinical |
| CHEMBL3407547 | 9.3 | IC50 | 0.5 | Clinical |
| CHEMBL4073202 | 9.24 | IC50 | 0.58 | Preclinical |
| CHEMBL5923261 | 9.2 | IC50 | 0.63 | Preclinical |
| CHEMBL5768893 | 9.17 | IC50 | 0.67 | Preclinical |
| CHEMBL5814783 | 9.17 | IC50 | 0.68 | Preclinical |
| CHEMBL5840411 | 9.16 | IC50 | 0.69 | Preclinical |
| CHEMBL5986273 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL4060253 | 9.12 | IC50 | 0.76 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 34 | 266 | 7.0 |
| cell-based format | 27 | 265 | 7.0 |
| assay format | 1 | 32 | 6.8 |