Protein O-GlcNAcase · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q8VIJ5. Use UniProt Q8VIJ5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8VIJ5 as the stable identity anchor, then attach disease evidence before program review.
Protein O-GlcNAcase
Review this target as Protein O-GlcNAcase, mapped to UniProt Q8VIJ5. Sequence length is 916 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protein O-GlcNAcase as ChEMBL target CHEMBL3351213, mapped to UniProt Q8VIJ5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Protein O-GlcNAcase |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q8VIJ5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Protein O-GlcNAcase |
| UniProt Accession | Q8VIJ5 |
| Component Type | Protein |
| Sequence Length | 916 aa |
Protein O-GlcNAcase
Review this target as Protein O-GlcNAcase, mapped to UniProt Q8VIJ5. Sequence length is 916 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4443587 | 8.77 | EC50 | 1.71 | Preclinical |
| CHEMBL5584048 | 8.16 | EC50 | 6.85 | Preclinical |
| CHEMBL5591513 | 8.13 | EC50 | 7.47 | Preclinical |
| CHEMBL4444446 | 7.97 | EC50 | 10.6 | Preclinical |
| CHEMBL5592023 | 7.97 | EC50 | 10.61 | Preclinical |
| CHEMBL5593511 | 7.88 | EC50 | 13.24 | Preclinical |
| CHEMBL1213603 | 7.87 | EC50 | 13.5 | Preclinical |
| CHEMBL5594139 | 7.68 | EC50 | 20.69 | Preclinical |
| CHEMBL5592978 | 7.65 | EC50 | 22.62 | Preclinical |
| CHEMBL5591099 | 7.61 | EC50 | 24.59 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 53 | 7.1 |
| single protein format | 1 | 1 | 7.3 |