Neuromedin-U receptor 1 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt O55040. Use UniProt O55040 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O55040 as the stable identity anchor, then attach disease evidence before program review.
Neuromedin-U receptor 1
Review this target as Neuromedin-U receptor 1, mapped to UniProt O55040. Sequence length is 428 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Neuromedin-U receptor 1 as ChEMBL target CHEMBL3351216, mapped to UniProt O55040. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Neuromedin-U receptor 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | O55040 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Neuromedin-U receptor 1 |
| UniProt Accession | O55040 |
| Component Type | Protein |
| Sequence Length | 428 aa |
Neuromedin-U receptor 1
Review this target as Neuromedin-U receptor 1, mapped to UniProt O55040. Sequence length is 428 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4088263 | 9.8 | EC50 | 0.16 | Preclinical |
| CHEMBL4068681 | 9.68 | EC50 | 0.21 | Preclinical |
| CHEMBL4095998 | 9.57 | EC50 | 0.27 | Preclinical |
| CHEMBL4097923 | 9.38 | EC50 | 0.42 | Preclinical |
| CHEMBL4098010 | 9.24 | EC50 | 0.57 | Preclinical |
| CHEMBL3356083 | 9.23 | EC50 | 0.59 | Preclinical |
| CHEMBL4073946 | 9.16 | EC50 | 0.69 | Preclinical |
| CHEMBL4099780 | 8.6 | EC50 | 2.5 | Preclinical |
| CHEMBL4059530 | 8.52 | EC50 | 3.0 | Preclinical |
| CHEMBL4079986 | 8.47 | EC50 | 3.4 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 17 | 7.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 22 | 8.4 |