Adenosine receptor A3 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P28647. Use UniProt P28647 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P28647 as the stable identity anchor, then attach disease evidence before program review.
Adenosine receptor A3
Review this target as Adenosine receptor A3, mapped to UniProt P28647. Sequence length is 320 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Adenosine receptor A3 as ChEMBL target CHEMBL3360, mapped to UniProt P28647. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Adenosine receptor A3 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P28647 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Adenosine receptor A3 |
| UniProt Accession | P28647 |
| Component Type | Protein |
| Sequence Length | 320 aa |
Adenosine receptor A3
Review this target as Adenosine receptor A3, mapped to UniProt P28647. Sequence length is 320 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL27376 | 9.77 | Kd | 0.17 | Preclinical |
| CHEMBL431733 | 9.48 | Ki | 0.33 | Clinical |
| CHEMBL608327 | 9.48 | Ki | 0.33 | Preclinical |
| CHEMBL2113400 | 9.48 | Ki | 0.33 | Preclinical |
| CHEMBL200732 | 9.42 | Ki | 0.38 | Preclinical |
| CHEMBL2368455 | 9.12 | Ki | 0.76 | Preclinical |
| CHEMBL2112157 | 9.06 | Ki | 0.87 | Preclinical |
| CHEMBL2113613 | 9.06 | Ki | 0.88 | Preclinical |
| CHEMBL175543 | 9.0 | Ki | 1.0 | Preclinical |
| CHEMBL133566 | 9.0 | Kd | 1.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 64 | 270 | 6.7 |
| single protein format | 31 | 54 | 7.3 |
| assay format | 15 | 59 | 5.9 |
| cell membrane format | 8 | 28 | 6.3 |
| tissue-based format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 10 | 1 | 7.1 |
| assay format | 3 | 4 | 4.8 |
| tissue-based format | 1 | 0 | — |