Tubulin beta chain · SINGLE PROTEIN · Bos taurus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q6B856. Use UniProt Q6B856 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q6B856 as the stable identity anchor, then attach disease evidence before program review.
Tubulin beta-2B chain
Review this target as Tubulin beta chain, mapped to UniProt Q6B856. ChEMBL maps the protein component as Tubulin beta-2B chain. Sequence length is 445 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Tubulin beta chain as ChEMBL target CHEMBL3394, mapped to UniProt Q6B856. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Tubulin beta chain is the right protein anchor across sources, using UniProt Q6B856 as the stable mapping.
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| Preferred Name | Tubulin beta chain |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | Q6B856 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tubulin beta-2B chain |
| UniProt Accession | Q6B856 |
| Component Type | Protein |
| Sequence Length | 445 aa |
Tubulin beta-2B chain
Review this target as Tubulin beta chain, mapped to UniProt Q6B856. ChEMBL maps the protein component as Tubulin beta-2B chain. Sequence length is 445 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL67 | 6.75 | Ki | 180.0 | Preclinical |
| CHEMBL343288 | 6.41 | IC50 | 390.0 | Preclinical |
| CHEMBL61 | 6.34 | IC50 | 460.0 | Approved |
| CHEMBL140220 | 6.28 | IC50 | 530.0 | Preclinical |
| CHEMBL140363 | 6.28 | IC50 | 530.0 | Preclinical |
| CHEMBL67 | 6.28 | IC50 | 530.0 | Preclinical |
| CHEMBL279142 | 6.24 | IC50 | 570.0 | Preclinical |
| CHEMBL14120 | 6.21 | IC50 | 610.0 | Preclinical |
| CHEMBL14782 | 6.21 | IC50 | 620.0 | Preclinical |
| CHEMBL73156 | 6.21 | IC50 | 620.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 14 | 37 | 5.3 |
| assay format | 9 | 18 | 5.2 |
| tissue-based format | 1 | 5 | 5.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 10 | 140 | 5.6 |