Use UniProt B9V8S1 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3395 Target Snapshot
Glutamate receptor ionotropic kainate 2 · SINGLE PROTEIN · Xenopus laevis
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As of 2026-09-14Protein identity stays anchored to UniProt B9V8S1. Use UniProt B9V8S1 as the stable identity anchor, then attach disease evidence before program review.
Glutamate receptor
Review this target as Glutamate receptor ionotropic kainate 2, mapped to UniProt B9V8S1. ChEMBL maps the protein component as Glutamate receptor. Sequence length is 908 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Glutamate receptor ionotropic kainate 2 as ChEMBL target CHEMBL3395, mapped to UniProt B9V8S1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Glutamate receptor ionotropic kainate 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Xenopus laevis |
| UniProt | B9V8S1 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glutamate receptor |
| UniProt Accession | B9V8S1 |
| Component Type | Protein |
| Sequence Length | 908 aa |
Glutamate receptor
How to read this target
Review this target as Glutamate receptor ionotropic kainate 2, mapped to UniProt B9V8S1. ChEMBL maps the protein component as Glutamate receptor. Sequence length is 908 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL29024 | 5.31 | EC50 | 4900.0 | Preclinical |
| CHEMBL28472 | 5.19 | EC50 | 6400.0 | Preclinical |
| CHEMBL27130 | 4.21 | EC50 | 61000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 4 assays, 3 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 3 | 4.9 |