Sodium channel protein type 2 subunit alpha · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P04775. Use UniProt P04775 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P04775 as the stable identity anchor, then attach disease evidence before program review.
Sodium channel protein type 2 subunit alpha
Review this target as Sodium channel protein type 2 subunit alpha, mapped to UniProt P04775. Sequence length is 2005 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sodium channel protein type 2 subunit alpha as ChEMBL target CHEMBL3399, mapped to UniProt P04775. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sodium channel protein type 2 subunit alpha |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P04775 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sodium channel protein type 2 subunit alpha |
| UniProt Accession | P04775 |
| Component Type | Protein |
| Sequence Length | 2005 aa |
Sodium channel protein type 2 subunit alpha
Review this target as Sodium channel protein type 2 subunit alpha, mapped to UniProt P04775. Sequence length is 2005 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3318149 | 8.55 | IC50 | 2.8 | Preclinical |
| CHEMBL525818 | 8.52 | Kd | 3.0 | Preclinical |
| CHEMBL3318150 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL3318148 | 8.46 | IC50 | 3.48 | Preclinical |
| CHEMBL507974 | 8.4 | IC50 | 4.0 | Clinical |
| CHEMBL2402969 | 8.28 | Kd | 5.3 | Preclinical |
| CHEMBL3318147 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL3318134 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL299668 | 8.05 | Ki | 9.0 | Preclinical |
| CHEMBL3318136 | 7.62 | IC50 | 24.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 27 | 78 | 6.2 |
| single protein format | 2 | 2 | 7.7 |
| assay format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 7 | 6.7 |
| assay format | 1 | 19 | 6.0 |
| tissue-based format | 1 | 18 | 5.2 |