Use UniProt Q13118 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3407312 Target Snapshot
Krueppel-like factor 10 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q13118. Use UniProt Q13118 as the stable identity anchor, then attach disease evidence before program review.
Krueppel-like factor 10
Review this target as Krueppel-like factor 10, mapped to UniProt Q13118. Sequence length is 480 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Krueppel-like factor 10 as ChEMBL target CHEMBL3407312, mapped to UniProt Q13118. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Krueppel-like factor 10 is the right protein anchor across sources, using UniProt Q13118 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Krueppel-like factor 10 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q13118 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Krueppel-like factor 10 |
| UniProt Accession | Q13118 |
| Component Type | Protein |
| Sequence Length | 480 aa |
Krueppel-like factor 10
How to read this target
Review this target as Krueppel-like factor 10, mapped to UniProt Q13118. Sequence length is 480 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1333704 | 5.0 | IC50 | 10000.0 | Preclinical |
| CHEMBL3410747 | 4.4 | IC50 | 40000.0 | Preclinical |
| CHEMBL2179992 | 4.37 | IC50 | 43000.0 | Preclinical |
| CHEMBL4580136 | 4.37 | IC50 | 43000.0 | Preclinical |
| CHEMBL1324 | 4.3 | IC50 | 50000.0 | Approved |
| CHEMBL641 | 4.0 | IC50 | 100000.0 | Approved |
| CHEMBL3410732 | 4.0 | IC50 | 100000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 10 assays, 9 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 0 | — |
| cell-based format | 4 | 9 | 4.3 |