Glutathione S-transferase A1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P08263. Use UniProt P08263 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P08263 as the stable identity anchor, then attach disease evidence before program review.
Glutathione S-transferase A1
Review this target as Glutathione S-transferase A1, mapped to UniProt P08263. Sequence length is 222 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Glutathione S-transferase A1 as ChEMBL target CHEMBL3409, mapped to UniProt P08263. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Glutathione S-transferase A1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P08263 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glutathione S-transferase A1 |
| UniProt Accession | P08263 |
| Component Type | Protein |
| Sequence Length | 222 aa |
Glutathione S-transferase A1
Review this target as Glutathione S-transferase A1, mapped to UniProt P08263. Sequence length is 222 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL211727 | 7.86 | IC50 | 13.7 | Preclinical |
| CHEMBL211916 | 7.84 | IC50 | 14.3 | Preclinical |
| CHEMBL212685 | 7.62 | IC50 | 24.0 | Preclinical |
| CHEMBL212097 | 7.49 | IC50 | 32.7 | Preclinical |
| CHEMBL209755 | 7.41 | IC50 | 39.3 | Preclinical |
| CHEMBL379437 | 7.28 | IC50 | 52.1 | Preclinical |
| CHEMBL216505 | 7.0 | IC50 | 98.9 | Preclinical |
| CHEMBL5169380 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL5178537 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL3310886 | 6.75 | IC50 | 180.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 17 | 5 | 5.2 |
| single protein format | 12 | 27 | 6.2 |
| cell-based format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 12 | 0 | — |