DNA polymerase catalytic subunit · SINGLE PROTEIN · Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5)
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As of 2026-09-14Protein identity stays anchored to UniProt P08546. Use UniProt P08546 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P08546 as the stable identity anchor, then attach disease evidence before program review.
DNA polymerase catalytic subunit
Review this target as DNA polymerase catalytic subunit, mapped to UniProt P08546. Sequence length is 1242 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats DNA polymerase catalytic subunit as ChEMBL target CHEMBL3414, mapped to UniProt P08546. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether DNA polymerase catalytic subunit is the right protein anchor across sources, using UniProt P08546 as the stable mapping.
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| Preferred Name | DNA polymerase catalytic subunit |
| Target Type | SINGLE PROTEIN |
| Organism | Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) |
| UniProt | P08546 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | DNA polymerase catalytic subunit |
| UniProt Accession | P08546 |
| Component Type | Protein |
| Sequence Length | 1242 aa |
DNA polymerase catalytic subunit
Review this target as DNA polymerase catalytic subunit, mapped to UniProt P08546. Sequence length is 1242 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL395623 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL3099827 | 7.66 | IC50 | 22.0 | Preclinical |
| CHEMBL3099826 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL247955 | 7.46 | IC50 | 35.0 | Preclinical |
| CHEMBL248363 | 7.43 | IC50 | 37.0 | Preclinical |
| CHEMBL3099825 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL3983250 | 7.23 | IC50 | 59.0 | Preclinical |
| CHEMBL248161 | 7.21 | IC50 | 61.0 | Preclinical |
| CHEMBL3985859 | 7.21 | IC50 | 62.0 | Preclinical |
| CHEMBL247355 | 7.19 | IC50 | 65.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 100 | 6.3 |