Macrophage-expressed gene 1 protein · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q2M385. Use UniProt Q2M385 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q2M385 as the stable identity anchor, then attach disease evidence before program review.
Macrophage-expressed gene 1 protein
Review this target as Macrophage-expressed gene 1 protein, mapped to UniProt Q2M385. Sequence length is 716 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Macrophage-expressed gene 1 protein as ChEMBL target CHEMBL3414409, mapped to UniProt Q2M385. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Macrophage-expressed gene 1 protein is the right protein anchor across sources, using UniProt Q2M385 as the stable mapping.
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| Preferred Name | Macrophage-expressed gene 1 protein |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q2M385 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Macrophage-expressed gene 1 protein |
| UniProt Accession | Q2M385 |
| Component Type | Protein |
| Sequence Length | 716 aa |
Macrophage-expressed gene 1 protein
Review this target as Macrophage-expressed gene 1 protein, mapped to UniProt Q2M385. Sequence length is 716 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL221137 | 6.68 | IC50 | 210.0 | Preclinical |
| CHEMBL221598 | 6.1 | IC50 | 800.0 | Preclinical |
| CHEMBL462801 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL3416163 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL3416165 | 5.8 | IC50 | 1600.0 | Preclinical |
| CHEMBL3416348 | 5.75 | IC50 | 1800.0 | Preclinical |
| CHEMBL462998 | 5.68 | IC50 | 2100.0 | Preclinical |
| CHEMBL29097 | 5.66 | IC50 | 2200.0 | Preclinical |
| CHEMBL3416164 | 5.51 | IC50 | 3100.0 | Preclinical |
| CHEMBL3416349 | 5.36 | IC50 | 4400.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 16 | 5.6 |
| single protein format | 1 | 1 | 6.7 |