Histone acetyltransferase RTT109 · SINGLE PROTEIN · Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
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As of 2026-09-14Protein identity stays anchored to UniProt Q07794. Use UniProt Q07794 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q07794 as the stable identity anchor, then attach disease evidence before program review.
Histone acetyltransferase RTT109
Review this target as Histone acetyltransferase RTT109, mapped to UniProt Q07794. Sequence length is 436 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Histone acetyltransferase RTT109 as ChEMBL target CHEMBL3414417, mapped to UniProt Q07794. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Histone acetyltransferase RTT109 |
| Target Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| UniProt | Q07794 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Histone acetyltransferase RTT109 |
| UniProt Accession | Q07794 |
| Component Type | Protein |
| Sequence Length | 436 aa |
Histone acetyltransferase RTT109
Review this target as Histone acetyltransferase RTT109, mapped to UniProt Q07794. Sequence length is 436 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1331211 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL2031566 | 6.82 | IC50 | 150.0 | Preclinical |
| CHEMBL3416552 | 6.58 | IC50 | 260.0 | Preclinical |
| CHEMBL3416318 | 6.35 | IC50 | 450.0 | Preclinical |
| CHEMBL3416536 | 6.28 | IC50 | 520.0 | Preclinical |
| CHEMBL1385343 | 6.19 | IC50 | 640.0 | Preclinical |
| CHEMBL2030281 | 6.17 | IC50 | 670.0 | Preclinical |
| CHEMBL3416321 | 6.11 | IC50 | 770.0 | Preclinical |
| CHEMBL3416335 | 6.09 | IC50 | 810.0 | Preclinical |
| CHEMBL3235887 | 6.04 | IC50 | 910.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 103 | 5.2 |