Thymidine kinase · SINGLE PROTEIN · Human herpesvirus 2
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As of 2026-09-14Protein identity stays anchored to UniProt Q6L709. Use UniProt Q6L709 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q6L709 as the stable identity anchor, then attach disease evidence before program review.
Thymidine kinase
Review this target as Thymidine kinase, mapped to UniProt Q6L709. Sequence length is 376 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Thymidine kinase as ChEMBL target CHEMBL3415, mapped to UniProt Q6L709. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Thymidine kinase is the right protein anchor across sources, using UniProt Q6L709 as the stable mapping.
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| Preferred Name | Thymidine kinase |
| Target Type | SINGLE PROTEIN |
| Organism | Human herpesvirus 2 |
| UniProt | Q6L709 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Thymidine kinase |
| UniProt Accession | Q6L709 |
| Component Type | Protein |
| Sequence Length | 376 aa |
Thymidine kinase
Review this target as Thymidine kinase, mapped to UniProt Q6L709. Sequence length is 376 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL288683 | 10.05 | IC50 | 0.09 | Preclinical |
| CHEMBL432111 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL290528 | 9.96 | IC50 | 0.11 | Preclinical |
| CHEMBL418258 | 9.96 | IC50 | 0.11 | Preclinical |
| CHEMBL45114 | 9.96 | IC50 | 0.11 | Preclinical |
| CHEMBL42459 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL47089 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL44047 | 9.85 | IC50 | 0.14 | Preclinical |
| CHEMBL46821 | 9.85 | IC50 | 0.14 | Preclinical |
| CHEMBL46884 | 9.85 | IC50 | 0.14 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 5 | 77 | 7.2 |
| cell-based format | 1 | 35 | 5.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |