Methionine aminopeptidase · SINGLE PROTEIN · Escherichia coli K-12
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As of 2026-09-13Protein identity stays anchored to UniProt P0AE18. Use UniProt P0AE18 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P0AE18 as the stable identity anchor, then attach disease evidence before program review.
Methionine aminopeptidase
Review this target as Methionine aminopeptidase, mapped to UniProt P0AE18. Sequence length is 264 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Methionine aminopeptidase as ChEMBL target CHEMBL3423, mapped to UniProt P0AE18. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Methionine aminopeptidase is the right protein anchor across sources, using UniProt P0AE18 as the stable mapping.
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| Preferred Name | Methionine aminopeptidase |
| Target Type | SINGLE PROTEIN |
| Organism | Escherichia coli K-12 |
| UniProt | P0AE18 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Methionine aminopeptidase |
| UniProt Accession | P0AE18 |
| Component Type | Protein |
| Sequence Length | 264 aa |
Methionine aminopeptidase
Review this target as Methionine aminopeptidase, mapped to UniProt P0AE18. Sequence length is 264 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL188263 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL188976 | 7.64 | IC50 | 23.0 | Preclinical |
| CHEMBL359683 | 7.62 | IC50 | 24.0 | Preclinical |
| CHEMBL188845 | 7.6 | IC50 | 25.0 | Preclinical |
| CHEMBL363943 | 7.55 | IC50 | 28.0 | Preclinical |
| CHEMBL180070 | 7.54 | IC50 | 29.0 | Preclinical |
| CHEMBL366071 | 7.48 | IC50 | 33.0 | Preclinical |
| CHEMBL371393 | 7.48 | IC50 | 33.0 | Preclinical |
| CHEMBL189688 | 7.47 | IC50 | 34.0 | Preclinical |
| CHEMBL362123 | 7.46 | IC50 | 35.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 15 | 164 | 5.8 |
| assay format | 4 | 56 | 5.9 |