ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P56528. Use UniProt P56528 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P56528 as the stable identity anchor, then attach disease evidence before program review.
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Review this target as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, mapped to UniProt P56528. Sequence length is 304 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 as ChEMBL target CHEMBL3425388, mapped to UniProt P56528. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P56528 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 |
| UniProt Accession | P56528 |
| Component Type | Protein |
| Sequence Length | 304 aa |
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Review this target as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, mapped to UniProt P56528. Sequence length is 304 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3426033 | 9.21 | IC50 | 0.62 | Preclinical |
| CHEMBL3426037 | 9.19 | IC50 | 0.65 | Preclinical |
| CHEMBL3426067 | 9.11 | IC50 | 0.78 | Preclinical |
| CHEMBL3426064 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL3426058 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL3426066 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL3426032 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL3426039 | 8.85 | IC50 | 1.4 | Preclinical |
| CHEMBL3426035 | 8.8 | IC50 | 1.6 | Preclinical |
| CHEMBL3426038 | 8.8 | IC50 | 1.6 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 4 | 7.7 |
| cell-based format | 1 | 83 | 7.7 |