Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha/beta · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P35913. Use UniProt P35913 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P35913 as the stable identity anchor, then attach disease evidence before program review.
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
Review this target as Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha/beta, mapped to UniProt P35913. ChEMBL maps the protein component as Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta. Sequence length is 854 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha/beta as ChEMBL target CHEMBL3430880, mapped to UniProt P35913. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha/beta is the right protein anchor across sources, using UniProt P35913 as the stable mapping.
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| Preferred Name | Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha/beta |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | P35913 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta |
| UniProt Accession | P35913 |
| Component Type | Protein |
| Sequence Length | 854 aa |
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
Review this target as Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha/beta, mapped to UniProt P35913. ChEMBL maps the protein component as Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta. Sequence length is 854 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5977186 | 6.21 | IC50 | 611.0 | Preclinical |
| CHEMBL6042932 | 6.01 | IC50 | 982.0 | Preclinical |
| CHEMBL6057973 | 5.92 | IC50 | 1200.0 | Preclinical |
| CHEMBL5842843 | 5.58 | IC50 | 2659.0 | Preclinical |
| CHEMBL5908735 | 5.52 | IC50 | 2990.0 | Preclinical |
| CHEMBL5866418 | 5.51 | IC50 | 3060.0 | Preclinical |
| CHEMBL5762359 | 5.48 | IC50 | 3290.0 | Preclinical |
| CHEMBL5773878 | 5.42 | IC50 | 3850.0 | Preclinical |
| CHEMBL5828480 | 5.12 | IC50 | 7623.0 | Preclinical |
| CHEMBL5945056 | 5.02 | IC50 | 9590.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 3 | 10 | 5.6 |
| assay format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |