Aurora kinase B/Inner centromere protein · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-15Protein identity stays anchored to UniProt Q96GD4. Use UniProt Q96GD4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q96GD4 as the stable identity anchor, then attach disease evidence before program review.
Aurora kinase B
Review this target as Aurora kinase B/Inner centromere protein, mapped to UniProt Q96GD4. ChEMBL maps the protein component as Aurora kinase B. Sequence length is 344 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Aurora kinase B/Inner centromere protein as ChEMBL target CHEMBL3430907, mapped to UniProt Q96GD4. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Aurora kinase B/Inner centromere protein is the right protein anchor across sources, using UniProt Q96GD4 as the stable mapping.
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| Preferred Name | Aurora kinase B/Inner centromere protein |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | Q96GD4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Aurora kinase B |
| UniProt Accession | Q96GD4 |
| Component Type | Protein |
| Sequence Length | 344 aa |
Aurora kinase B
Review this target as Aurora kinase B/Inner centromere protein, mapped to UniProt Q96GD4. ChEMBL maps the protein component as Aurora kinase B. Sequence length is 344 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3544932 | 10.7 | Ki | 0.02 | Preclinical |
| CHEMBL1090479 | 9.42 | Ki | 0.38 | Preclinical |
| CHEMBL587029 | 9.3 | IC50 | 0.5012 | Preclinical |
| CHEMBL1090832 | 9.21 | IC50 | 0.61 | Preclinical |
| CHEMBL483158 | 8.96 | IC50 | 1.1 | Clinical |
| CHEMBL3600873 | 8.83 | IC50 | 1.49 | Preclinical |
| CHEMBL1089116 | 8.7 | IC50 | 1.995 | Preclinical |
| CHEMBL3663741 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL1090479 | 8.5 | IC50 | 3.162 | Preclinical |
| CHEMBL3663733 | 8.4 | IC50 | 4.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 29 | 117 | 6.7 |
| cell-based format | 8 | 16 | 7.3 |
| assay format | 1 | 18 | 4.6 |