Aurora kinase B/Receptor-type tyrosine-protein kinase · SELECTIVITY GROUP · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P36888. Use UniProt P36888 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P36888 as the stable identity anchor, then attach disease evidence before program review.
Receptor-type tyrosine-protein kinase FLT3
Review this target as Aurora kinase B/Receptor-type tyrosine-protein kinase, mapped to UniProt P36888. ChEMBL maps the protein component as Receptor-type tyrosine-protein kinase FLT3. Sequence length is 993 aa.
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This review treats Aurora kinase B/Receptor-type tyrosine-protein kinase as ChEMBL target CHEMBL3430908, mapped to UniProt P36888. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Aurora kinase B/Receptor-type tyrosine-protein kinase is the right protein anchor across sources, using UniProt P36888 as the stable mapping.
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| Preferred Name | Aurora kinase B/Receptor-type tyrosine-protein kinase |
| Target Type | SELECTIVITY GROUP |
| Organism | Homo sapiens |
| UniProt | P36888 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Receptor-type tyrosine-protein kinase FLT3 |
| UniProt Accession | P36888 |
| Component Type | Protein |
| Sequence Length | 993 aa |
Receptor-type tyrosine-protein kinase FLT3
Review this target as Aurora kinase B/Receptor-type tyrosine-protein kinase, mapped to UniProt P36888. ChEMBL maps the protein component as Receptor-type tyrosine-protein kinase FLT3. Sequence length is 993 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5176837 | 10.92 | Kd | 0.012 | Preclinical |
| CHEMBL2105717 | 8.54 | IC50 | 2.86 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 1 | 10.9 |
| cell-based format | 1 | 1 | 8.5 |