Glutamate receptor ionotropic, NMDA 2B · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt Q01097. Use UniProt Q01097 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q01097 as the stable identity anchor, then attach disease evidence before program review.
Glutamate receptor ionotropic, NMDA 2B
Review this target as Glutamate receptor ionotropic, NMDA 2B, mapped to UniProt Q01097. Sequence length is 1482 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Glutamate receptor ionotropic, NMDA 2B as ChEMBL target CHEMBL3442, mapped to UniProt Q01097. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Glutamate receptor ionotropic, NMDA 2B |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q01097 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glutamate receptor ionotropic, NMDA 2B |
| UniProt Accession | Q01097 |
| Component Type | Protein |
| Sequence Length | 1482 aa |
Glutamate receptor ionotropic, NMDA 2B
Review this target as Glutamate receptor ionotropic, NMDA 2B, mapped to UniProt Q01097. Sequence length is 1482 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL282433 | 9.22 | Ki | 0.6 | Preclinical |
| CHEMBL4086848 | 9.2 | IC50 | 0.631 | Preclinical |
| CHEMBL4094573 | 9.2 | IC50 | 0.631 | Preclinical |
| CHEMBL493054 | 9.1 | Ki | 0.8 | Preclinical |
| CHEMBL4078903 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4095807 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4526884 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4534333 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4059534 | 8.7 | IC50 | 1.995 | Preclinical |
| CHEMBL4583880 | 8.7 | IC50 | 1.995 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 7 | 76 | 7.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 1 | 4.3 |