Neuronal acetylcholine receptor subunit alpha-10 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q9JLB5. Use UniProt Q9JLB5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9JLB5 as the stable identity anchor, then attach disease evidence before program review.
Neuronal acetylcholine receptor subunit alpha-10
Review this target as Neuronal acetylcholine receptor subunit alpha-10, mapped to UniProt Q9JLB5. Sequence length is 447 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Neuronal acetylcholine receptor subunit alpha-10 as ChEMBL target CHEMBL3461, mapped to UniProt Q9JLB5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Neuronal acetylcholine receptor subunit alpha-10 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q9JLB5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Neuronal acetylcholine receptor subunit alpha-10 |
| UniProt Accession | Q9JLB5 |
| Component Type | Protein |
| Sequence Length | 447 aa |
Neuronal acetylcholine receptor subunit alpha-10
Review this target as Neuronal acetylcholine receptor subunit alpha-10, mapped to UniProt Q9JLB5. Sequence length is 447 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL305674 | 8.51 | Ki | 3.1 | Preclinical |
| CHEMBL74249 | 8.3 | Ki | 5.0 | Preclinical |
| CHEMBL72198 | 7.89 | Ki | 13.0 | Preclinical |
| CHEMBL72502 | 7.84 | Ki | 14.4 | Preclinical |
| CHEMBL74045 | 7.84 | Ki | 14.3 | Preclinical |
| CHEMBL73294 | 7.76 | Ki | 17.3 | Preclinical |
| CHEMBL73141 | 7.75 | Ki | 18.0 | Preclinical |
| CHEMBL73293 | 7.75 | Ki | 17.6 | Preclinical |
| CHEMBL75277 | 7.75 | Ki | 18.0 | Preclinical |
| CHEMBL74845 | 7.71 | Ki | 19.3 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 44 | 6.7 |
| single protein format | 1 | 1 | 5.9 |
| tissue-based format | 1 | 0 | — |