Human immunodeficiency virus type 2 integrase · SINGLE PROTEIN · Human immunodeficiency virus 2
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As of 2026-09-14Protein identity stays anchored to UniProt P89582. Use UniProt P89582 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P89582 as the stable identity anchor, then attach disease evidence before program review.
Integrase
Review this target as Human immunodeficiency virus type 2 integrase, mapped to UniProt P89582. ChEMBL maps the protein component as Integrase. Sequence length is 95 aa.
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This review treats Human immunodeficiency virus type 2 integrase as ChEMBL target CHEMBL3463, mapped to UniProt P89582. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Human immunodeficiency virus type 2 integrase |
| Target Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus 2 |
| UniProt | P89582 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Integrase |
| UniProt Accession | P89582 |
| Component Type | Protein |
| Sequence Length | 95 aa |
Integrase
Review this target as Human immunodeficiency virus type 2 integrase, mapped to UniProt P89582. ChEMBL maps the protein component as Integrase. Sequence length is 95 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1229211 | 8.64 | EC50 | 2.3 | Approved |
| CHEMBL177126 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL293914 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL175266 | 5.82 | IC50 | 1500.0 | Preclinical |
| CHEMBL174366 | 5.8 | IC50 | 1600.0 | Preclinical |
| CHEMBL366356 | 5.6 | IC50 | 2500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 7 | 6 | 6.2 |