Nitric oxide synthase, inducible · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P29477. Use UniProt P29477 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P29477 as the stable identity anchor, then attach disease evidence before program review.
Nitric oxide synthase, inducible
Review this target as Nitric oxide synthase, inducible, mapped to UniProt P29477. Sequence length is 1144 aa.
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This review treats Nitric oxide synthase, inducible as ChEMBL target CHEMBL3464, mapped to UniProt P29477. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Nitric oxide synthase, inducible |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P29477 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Nitric oxide synthase, inducible |
| UniProt Accession | P29477 |
| Component Type | Protein |
| Sequence Length | 1144 aa |
Nitric oxide synthase, inducible
Review this target as Nitric oxide synthase, inducible, mapped to UniProt P29477. Sequence length is 1144 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL224752 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL126713 | 8.74 | Ki | 1.8 | Preclinical |
| CHEMBL105792 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL1944717 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL594682 | 8.3 | Ki | 5.0 | Preclinical |
| CHEMBL321691 | 8.28 | Ki | 5.2 | Preclinical |
| CHEMBL2447968 | 8.15 | Ki | 7.0 | Preclinical |
| CHEMBL1800346 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL480419 | 7.85 | Ki | 14.0 | Preclinical |
| CHEMBL491923 | 7.85 | EC50 | 14.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 96 | 241 | 5.3 |
| single protein format | 68 | 321 | 5.3 |
| assay format | 34 | 245 | 5.0 |
| organism-based format | 3 | 4 | 7.3 |
| tissue-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 19 | 11 | 5.9 |
| cell-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 7 | 59 | 5.0 |