Falcipain 2B · SINGLE PROTEIN · Plasmodium falciparum
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As of 2026-09-14Protein identity stays anchored to UniProt Q3HTL5. Use UniProt Q3HTL5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q3HTL5 as the stable identity anchor, then attach disease evidence before program review.
Falcipain 2B
Review this target as Falcipain 2B, mapped to UniProt Q3HTL5. Sequence length is 241 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Falcipain 2B as ChEMBL target CHEMBL3488, mapped to UniProt Q3HTL5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Falcipain 2B |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum |
| UniProt | Q3HTL5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Falcipain 2B |
| UniProt Accession | Q3HTL5 |
| Component Type | Protein |
| Sequence Length | 241 aa |
Falcipain 2B
Review this target as Falcipain 2B, mapped to UniProt Q3HTL5. Sequence length is 241 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL423112 | 5.3 | IC50 | 5000.0 | Preclinical |
| CHEMBL207102 | 5.02 | IC50 | 9530.0 | Preclinical |
| CHEMBL209147 | 4.95 | IC50 | 11190.0 | Preclinical |
| CHEMBL378475 | 4.92 | IC50 | 11950.0 | Preclinical |
| CHEMBL207117 | 4.85 | IC50 | 14010.0 | Preclinical |
| CHEMBL382121 | 4.83 | IC50 | 14700.0 | Preclinical |
| CHEMBL377886 | 4.75 | IC50 | 17940.0 | Preclinical |
| CHEMBL210211 | 4.71 | IC50 | 19310.0 | Preclinical |
| CHEMBL377557 | 4.7 | IC50 | 19790.0 | Preclinical |
| CHEMBL437308 | 4.67 | IC50 | 21390.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 11 | 4.8 |