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Target Snapshot

CHEMBL349 Target Snapshot

Enterobacter cloacae · ORGANISM · Enterobacter cloacae

4,183Compounds
1,177Assays
8Approved Drugs
101.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Enterobacter cloacae as ChEMBL target CHEMBL349. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Enterobacter cloacae
ORGANISM · Enterobacter cloacae
As of 2026-09-14
ChEMBL target ID
CHEMBL349
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Enterobacter cloacae still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelEnterobacter cloacae
UniProt AccessionN/A

Enterobacter cloacae

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Enterobacter cloacae.

Review nameEnterobacter cloacae
OrganismEnterobacter cloacae
Clinical Profile

Clinical Phase Distribution

8
Approved
1
Phase III
1
Phase II
Assay Mix

Activity Type Distribution

IC5012.0
EC5089.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL304733 8.7 IC50 2.0 Preclinical
CHEMBL69141 6.52 IC50 300.0 Preclinical
CHEMBL6461 6.0 IC50 1000.0 Preclinical
CHEMBL1434 5.82 EC50 1500.0 Approved
CHEMBL124960 5.7 IC50 2000.0 Preclinical
CHEMBL130 5.66 EC50 2200.0 Approved
CHEMBL333078 5.4 IC50 4000.0 Preclinical
CHEMBL374478 5.21 EC50 6200.0 Approved
CHEMBL1454910 5.18 EC50 6600.0 Approved
CHEMBL122209 5.1 IC50 8000.0 Preclinical
Distribution

pChEMBL Value Distribution

7
5.0
3
5.5
1
6.0
1
6.5
0
7.0
0
7.5
0
8.0
1
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

1,195
Total Assays
24
Tested Compounds
2
Assay Types
Functional — 1,162 assays, 24 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 1,138 24 5.1
assay format 24 0
ADME — 33 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 33 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine