Beta-lactamase class C · SINGLE PROTEIN · Enterobacter cloacae
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As of 2026-09-14Protein identity stays anchored to UniProt Q59401. Use UniProt Q59401 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q59401 as the stable identity anchor, then attach disease evidence before program review.
Beta-lactamase
Review this target as Beta-lactamase class C, mapped to UniProt Q59401. ChEMBL maps the protein component as Beta-lactamase. Sequence length is 384 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-lactamase class C as ChEMBL target CHEMBL3499, mapped to UniProt Q59401. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Beta-lactamase class C is the right protein anchor across sources, using UniProt Q59401 as the stable mapping.
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| Preferred Name | Beta-lactamase class C |
| Target Type | SINGLE PROTEIN |
| Organism | Enterobacter cloacae |
| UniProt | Q59401 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-lactamase |
| UniProt Accession | Q59401 |
| Component Type | Protein |
| Sequence Length | 384 aa |
Beta-lactamase
Review this target as Beta-lactamase class C, mapped to UniProt Q59401. ChEMBL maps the protein component as Beta-lactamase. Sequence length is 384 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL353613 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL355558 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL353422 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL355288 | 7.54 | IC50 | 29.0 | Preclinical |
| CHEMBL354754 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL166730 | 7.41 | IC50 | 39.0 | Preclinical |
| CHEMBL169154 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL422212 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL433726 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL353004 | 6.78 | IC50 | 165.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 10 | 40 | 6.1 |