Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL351 Target Snapshot

Salmonella typhimurium · ORGANISM · Salmonella enterica subsp. enterica serovar Typhimurium

Back to Search Search this target Browse approvals Evidence Card
5,983Compounds
3,572Assays
4Approved Drugs
741.0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Research home Demo workspace
Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-15

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-15
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Salmonella typhimurium as ChEMBL target CHEMBL351. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Salmonella typhimurium
ORGANISM · Salmonella enterica subsp. enterica serovar Typhimurium
As of 2026-09-15
ChEMBL target ID
CHEMBL351
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-15
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-15
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Salmonella typhimurium still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameSalmonella typhimurium
Target TypeORGANISM
OrganismSalmonella enterica subsp. enterica serovar Typhimurium
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSalmonella typhimurium
UniProt AccessionN/A

Salmonella typhimurium

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Salmonella typhimurium.

Review nameSalmonella typhimurium
OrganismSalmonella enterica subsp. enterica serovar Typhimurium
Clinical Profile

Clinical Phase Distribution

4
Approved
1
Phase I
Assay Mix

Activity Type Distribution

IC50619.0
EC50122.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL8 7.22 EC50 60.0 Approved
CHEMBL1164713 7.05 IC50 89.0 Preclinical
CHEMBL1164712 7.03 IC50 94.0 Preclinical
CHEMBL5179133 6.92 IC50 120.0 Preclinical
CHEMBL1650595 6.7 IC50 200.0 Preclinical
CHEMBL386394 6.7 IC50 200.0 Preclinical
CHEMBL567183 6.7 IC50 200.0 Preclinical
CHEMBL5171589 6.66 EC50 220.0 Preclinical
CHEMBL5408093 6.42 EC50 380.0 Preclinical
CHEMBL376022 6.4 IC50 400.0 Preclinical
Distribution

pChEMBL Value Distribution

133
5.0
56
5.5
27
6.0
10
6.5
3
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

CIPROFLOXACIN
CHEMBL8
Approved 1987
Properties Compare Identifier
Assay Landscape

Assay Landscape

3,646
Total Assays
458
Tested Compounds
4
Assay Types
Toxicity — 2,027 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 1,787 0 —
assay format 240 0 —
Functional — 1,562 assays, 458 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 1,545 458 5.0
assay format 17 0 —
ADME — 55 assays, 40 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 52 40 4.4
assay format 3 0 —
Binding — 2 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 2 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine