Vascular endothelial growth factor receptor 1 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P35969. Use UniProt P35969 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P35969 as the stable identity anchor, then attach disease evidence before program review.
Vascular endothelial growth factor receptor 1
Review this target as Vascular endothelial growth factor receptor 1, mapped to UniProt P35969. Sequence length is 1333 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Vascular endothelial growth factor receptor 1 as ChEMBL target CHEMBL3516, mapped to UniProt P35969. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Vascular endothelial growth factor receptor 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P35969 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Vascular endothelial growth factor receptor 1 |
| UniProt Accession | P35969 |
| Component Type | Protein |
| Sequence Length | 1333 aa |
Vascular endothelial growth factor receptor 1
Review this target as Vascular endothelial growth factor receptor 1, mapped to UniProt P35969. Sequence length is 1333 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1289494 | 9.68 | IC50 | 0.21 | Approved |
| CHEMBL86943 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL313433 | 6.85 | IC50 | 140.0 | Preclinical |
| CHEMBL316008 | 6.75 | IC50 | 180.0 | Preclinical |
| CHEMBL89483 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL86755 | 6.41 | IC50 | 390.0 | Preclinical |
| CHEMBL89363 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL328710 | 6.1 | IC50 | 800.0 | Preclinical |
| CHEMBL330321 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL276711 | 5.98 | IC50 | 1040.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 6 | 6.2 |
| single protein format | 1 | 37 | 5.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 1 | 0 | — |