Receptor-type tyrosine-protein phosphatase F · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P10586. Use UniProt P10586 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P10586 as the stable identity anchor, then attach disease evidence before program review.
Receptor-type tyrosine-protein phosphatase F
Review this target as Receptor-type tyrosine-protein phosphatase F, mapped to UniProt P10586. Sequence length is 1907 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Receptor-type tyrosine-protein phosphatase F as ChEMBL target CHEMBL3521, mapped to UniProt P10586. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Receptor-type tyrosine-protein phosphatase F |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P10586 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Receptor-type tyrosine-protein phosphatase F |
| UniProt Accession | P10586 |
| Component Type | Protein |
| Sequence Length | 1907 aa |
Receptor-type tyrosine-protein phosphatase F
Review this target as Receptor-type tyrosine-protein phosphatase F, mapped to UniProt P10586. Sequence length is 1907 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL506661 | 7.18 | IC50 | 66.0 | Preclinical |
| CHEMBL556636 | 6.42 | IC50 | 382.3 | Preclinical |
| CHEMBL564699 | 6.42 | IC50 | 380.0 | Preclinical |
| CHEMBL1241315 | 6.39 | IC50 | 410.0 | Preclinical |
| CHEMBL324232 | 6.38 | IC50 | 420.0 | Preclinical |
| CHEMBL549372 | 6.34 | IC50 | 458.3 | Preclinical |
| CHEMBL556076 | 6.31 | IC50 | 493.0 | Preclinical |
| CHEMBL550662 | 6.2 | IC50 | 624.7 | Preclinical |
| CHEMBL200117 | 6.16 | IC50 | 690.0 | Preclinical |
| CHEMBL570779 | 6.12 | IC50 | 765.3 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 121 | 118 | 5.2 |
| assay format | 12 | 10 | 4.8 |
| cell-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |