Tissue alpha-L-fucosidase · SINGLE PROTEIN · Bos taurus
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As of 2026-09-14Protein identity stays anchored to UniProt Q2KIM0. Use UniProt Q2KIM0 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q2KIM0 as the stable identity anchor, then attach disease evidence before program review.
Tissue alpha-L-fucosidase
Review this target as Tissue alpha-L-fucosidase, mapped to UniProt Q2KIM0. Sequence length is 468 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Tissue alpha-L-fucosidase as ChEMBL target CHEMBL3545, mapped to UniProt Q2KIM0. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Tissue alpha-L-fucosidase |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | Q2KIM0 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tissue alpha-L-fucosidase |
| UniProt Accession | Q2KIM0 |
| Component Type | Protein |
| Sequence Length | 468 aa |
Tissue alpha-L-fucosidase
Review this target as Tissue alpha-L-fucosidase, mapped to UniProt Q2KIM0. Sequence length is 468 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL203969 | 9.0 | Ki | 1.0 | Preclinical |
| CHEMBL383067 | 9.0 | Ki | 1.0 | Preclinical |
| CHEMBL596048 | 9.0 | Ki | 1.0 | Preclinical |
| CHEMBL314772 | 8.77 | Ki | 1.7 | Preclinical |
| CHEMBL314772 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL87474 | 8.28 | Ki | 5.3 | Preclinical |
| CHEMBL593679 | 8.0 | Ki | 10.0 | Preclinical |
| CHEMBL2442786 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL2442784 | 7.68 | IC50 | 21.0 | Preclinical |
| CHEMBL2442783 | 7.58 | IC50 | 26.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 41 | 55 | 6.5 |
| tissue-based format | 9 | 25 | 4.3 |
| assay format | 1 | 0 | — |