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Target Snapshot

CHEMBL3548 Target Snapshot

Glycylpeptide N-tetradecanoyltransferase · SINGLE PROTEIN · Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

115Compounds
7Assays
0Approved Drugs
146.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt P30418. Use UniProt P30418 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P30418 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Glycylpeptide N-tetradecanoyltransferase as ChEMBL target CHEMBL3548, mapped to UniProt P30418. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Glycylpeptide N-tetradecanoyltransferase
SINGLE PROTEIN · Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
As of 2026-09-13
ChEMBL target ID
CHEMBL3548
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
P30418
Glycylpeptide N-tetradecanoyltransferase
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Glycylpeptide N-tetradecanoyltransferase is the right protein anchor across sources, using UniProt P30418 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelGlycylpeptide N-tetradecanoyltransferase
UniProt AccessionP30418
Component TypeProtein
Sequence Length451 aa

Glycylpeptide N-tetradecanoyltransferase

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Glycylpeptide N-tetradecanoyltransferase, mapped to UniProt P30418. Sequence length is 451 aa.

Mapped IDP30418
Review nameGlycylpeptide N-tetradecanoyltransferase
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Assay Mix

Activity Type Distribution

IC50144.0
KI2.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL170807 9.41 IC50 0.39 Preclinical
CHEMBL253804 9.31 IC50 0.49 Preclinical
CHEMBL3220375 9.31 IC50 0.49 Preclinical
CHEMBL2262498 9.0 IC50 1.0 Preclinical
CHEMBL254011 8.64 IC50 2.3 Preclinical
CHEMBL400892 8.62 IC50 2.4 Preclinical
CHEMBL2262499 8.52 IC50 3.0 Preclinical
CHEMBL254010 8.48 IC50 3.3 Preclinical
CHEMBL2262503 8.43 IC50 3.7 Preclinical
CHEMBL2262507 8.28 IC50 5.2 Preclinical
Distribution

pChEMBL Value Distribution

9
5.0
12
5.5
16
6.0
17
6.5
9
7.0
6
7.5
10
8.0
3
8.5
4
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

7
Total Assays
96
Tested Compounds
1
Assay Types
Binding — 7 assays, 96 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 7 96 6.6

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine