2-heptyl-4(1H)-quinolone synthase PqsD · SINGLE PROTEIN · Pseudomonas aeruginosa
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As of 2026-09-14Protein identity stays anchored to UniProt A0A0C7ACN7. Use UniProt A0A0C7ACN7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt A0A0C7ACN7 as the stable identity anchor, then attach disease evidence before program review.
3-oxoacyl-ACP synthase
Review this target as 2-heptyl-4(1H)-quinolone synthase PqsD, mapped to UniProt A0A0C7ACN7. ChEMBL maps the protein component as 3-oxoacyl-ACP synthase. Sequence length is 337 aa.
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This review treats 2-heptyl-4(1H)-quinolone synthase PqsD as ChEMBL target CHEMBL3559673, mapped to UniProt A0A0C7ACN7. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 2-heptyl-4(1H)-quinolone synthase PqsD |
| Target Type | SINGLE PROTEIN |
| Organism | Pseudomonas aeruginosa |
| UniProt | A0A0C7ACN7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 3-oxoacyl-ACP synthase |
| UniProt Accession | A0A0C7ACN7 |
| Component Type | Protein |
| Sequence Length | 337 aa |
3-oxoacyl-ACP synthase
Review this target as 2-heptyl-4(1H)-quinolone synthase PqsD, mapped to UniProt A0A0C7ACN7. ChEMBL maps the protein component as 3-oxoacyl-ACP synthase. Sequence length is 337 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3414805 | 6.85 | IC50 | 140.0 | Preclinical |
| CHEMBL3414806 | 6.44 | IC50 | 360.0 | Preclinical |
| CHEMBL3086445 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL2413670 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL4292096 | 5.77 | IC50 | 1700.0 | Preclinical |
| CHEMBL4453677 | 5.77 | IC50 | 1700.0 | Preclinical |
| CHEMBL369485 | 5.7 | IC50 | 2000.0 | Preclinical |
| CHEMBL3414804 | 5.57 | IC50 | 2700.0 | Preclinical |
| CHEMBL3414797 | 5.42 | IC50 | 3800.0 | Preclinical |
| CHEMBL3414794 | 5.3 | IC50 | 5000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 7 | 34 | 5.1 |
| single protein format | 4 | 7 | 4.9 |
| cell-based format | 3 | 0 | — |