2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase · SINGLE PROTEIN · Staphylococcus aureus
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As of 2026-09-14Protein identity stays anchored to UniProt X5EH84. Use UniProt X5EH84 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt X5EH84 as the stable identity anchor, then attach disease evidence before program review.
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
Review this target as 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase, mapped to UniProt X5EH84. ChEMBL maps the protein component as 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase. Sequence length is 158 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase as ChEMBL target CHEMBL3559681, mapped to UniProt X5EH84. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase is the right protein anchor across sources, using UniProt X5EH84 as the stable mapping.
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| Preferred Name | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase |
| Target Type | SINGLE PROTEIN |
| Organism | Staphylococcus aureus |
| UniProt | X5EH84 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase |
| UniProt Accession | X5EH84 |
| Component Type | Protein |
| Sequence Length | 158 aa |
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
Review this target as 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase, mapped to UniProt X5EH84. ChEMBL maps the protein component as 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase. Sequence length is 158 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3817872 | 6.92 | Kd | 120.0 | Preclinical |
| CHEMBL3818561 | 6.68 | Kd | 210.0 | Preclinical |
| CHEMBL3819387 | 6.66 | Kd | 220.0 | Preclinical |
| CHEMBL3818521 | 6.58 | Kd | 260.0 | Preclinical |
| CHEMBL3818609 | 6.54 | Kd | 290.0 | Preclinical |
| CHEMBL3819104 | 6.52 | Kd | 300.0 | Preclinical |
| CHEMBL3819161 | 6.52 | Kd | 300.0 | Preclinical |
| CHEMBL3818783 | 6.42 | Kd | 380.0 | Preclinical |
| CHEMBL3359162 | 6.35 | Kd | 450.0 | Preclinical |
| CHEMBL3818011 | 6.33 | Kd | 470.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 11 | 60 | 5.6 |