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Target Snapshot

CHEMBL3559704 Target Snapshot

Taste receptor type 2 member 10 · SINGLE PROTEIN · Homo sapiens

13Compounds
38Assays
1Approved Drugs
10.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q9NYW0. Use UniProt Q9NYW0 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9NYW0 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Taste receptor type 2 member 10 as ChEMBL target CHEMBL3559704, mapped to UniProt Q9NYW0. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Taste receptor type 2 member 10
SINGLE PROTEIN · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL3559704
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q9NYW0
Taste receptor type 2 member 10
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Taste receptor type 2 member 10 is the right protein anchor across sources, using UniProt Q9NYW0 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelTaste receptor type 2 member 10
UniProt AccessionQ9NYW0
Component TypeProtein
Sequence Length307 aa

Taste receptor type 2 member 10

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Taste receptor type 2 member 10, mapped to UniProt Q9NYW0. Sequence length is 307 aa.

Mapped IDQ9NYW0
Review nameTaste receptor type 2 member 10
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

1
Approved
1
Phase II
Assay Mix

Activity Type Distribution

EC5010.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL434 8.31 EC50 4.9 Approved
CHEMBL4440983 5.56 EC50 2740.0 Preclinical
CHEMBL227934 5.3 EC50 5000.0 Preclinical
CHEMBL4582048 4.6 EC50 25200.0 Preclinical
CHEMBL501756 4.22 EC50 60000.0 Preclinical
CHEMBL6067658 4.16 EC50 70000.0 Clinical
Distribution

pChEMBL Value Distribution

2
5.0
1
5.5
0
6.0
0
6.5
0
7.0
0
7.5
1
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

ISOPROTERENOL
CHEMBL434
Approved 1956
Assay Landscape

Assay Landscape

38
Total Assays
6
Tested Compounds
1
Assay Types
Functional — 38 assays, 6 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 38 6 5.1

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine