Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL3562161 Target Snapshot

Amino acid transporter · SINGLE PROTEIN · Rattus norvegicus

201Compounds
14Assays
1Approved Drugs
67.0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q9Z1J7. Use UniProt Q9Z1J7 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9Z1J7 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Amino acid transporter as ChEMBL target CHEMBL3562161, mapped to UniProt Q9Z1J7. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Amino acid transporter
SINGLE PROTEIN · Rattus norvegicus
As of 2026-09-14
ChEMBL target ID
CHEMBL3562161
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q9Z1J7
Amino acid transporter
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Amino acid transporter is the right protein anchor across sources, using UniProt Q9Z1J7 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelAmino acid transporter
UniProt AccessionQ9Z1J7
Component TypeProtein
Sequence Length539 aa

Amino acid transporter

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Amino acid transporter, mapped to UniProt Q9Z1J7. Sequence length is 539 aa.

Mapped IDQ9Z1J7
Review nameAmino acid transporter
OrganismRattus norvegicus
Clinical Profile

Clinical Phase Distribution

1
Approved
1
Phase III
Assay Mix

Activity Type Distribution

IC5053.0
KI14.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL3753869 5.89 IC50 1300.0 Preclinical
CHEMBL3752249 5.75 IC50 1800.0 Preclinical
CHEMBL4085113 5.52 Ki 3000.0 Preclinical
CHEMBL3752210 5.48 IC50 3300.0 Preclinical
CHEMBL3754498 5.29 IC50 5100.0 Preclinical
CHEMBL3752103 5.08 IC50 8400.0 Preclinical
CHEMBL3753592 5.06 IC50 8700.0 Preclinical
CHEMBL3754053 5.05 IC50 9000.0 Preclinical
CHEMBL3752700 4.98 IC50 10500.0 Preclinical
CHEMBL3754059 4.95 IC50 11200.0 Preclinical
Distribution

pChEMBL Value Distribution

5
5.0
3
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

14
Total Assays
48
Tested Compounds
1
Assay Types
Binding — 14 assays, 48 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 14 48 4.6

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine